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DOI: 10.1016/j.apsb.2023.09.012. Inflammatory bowel disease (IBD) is a formidable disease due to its complex pathogenesis. Macrophages, as a major immune cell population in IBD, are crucial for gut homeostasis. However, it is still unveiled how macrophages modulate IBD. Here, we found that LIM domain only 7 (LMO7) was downregulated..
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PDLIM7 (PDZ And LIM Domain 7) is a Protein Coding gene. Diseases associated with PDLIM7 include Lymphoepithelioma-Like Carcinoma and Hodgkin's Granuloma . Among its related pathways are Nervous system development and GDNF-Family Ligands and Receptor Interactions . An important paralog of this gene is PDLIM5.
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Model of the protein LIM domain only 7 (LMO7) feedback regulation of... Download Scientific
The LIM domain, which is defined by a conserved cysteine-rich sequence, is a modular protein-binding interface that is found in numerous eukaryotic proteins. The LIM sequence specifies a double.
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Lmo7 positively regulates many EDMD-relevant genes (including emerin), and is feedback-regulated by binding to emerin. This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different.
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PDLIM7. PDZ and LIM domain protein 7 is a protein that in humans is encoded by the PDLIM7 gene. [5] [6] The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription.
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LMO7 (LIM Domain 7) is a Protein Coding gene. Diseases associated with LMO7 include Townes-Brocks Syndrome and Cardiomyopathy, Dilated, 1Dd.Among its related pathways are Class I MHC mediated antigen processing and presentation and Signaling by ALK in cancer.Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity and actinin binding.
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LIM domains are protein structural domains, composed of two contiguous zinc fingers, separated by a two-amino acid residue hydrophobic linker. The domain name is an acronym of the three genes in which it was first identified (LIN-11, Isl-1 and MEC-3). LIM is a protein interaction domain that is involved in binding to many structurally and functionally diverse partners.
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The LIM domain only protein 7 (LMO7), a member of the PDZ and LIM domain-containing protein family is a candidate gene with possible roles in embryonic development and breast cancer progression. LMO7 has been linked to actin cytoskeleton organization through nectin/afadin and to cell-cell adhesion by means of E-cadherin/catenin. In addition.
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From the Intel's manual - Instruction Set Reference, the JE and JZ have the same opcode (74 for rel8 / 0F 84 for rel 16/32) also JNE and JNZ (75 for rel8 / 0F 85 for rel 16/32) share opcodes.. JE and JZ they both check for the ZF (or zero flag), although the manual differs slightly in the descriptions of the first JE rel8 and JZ rel8 ZF usage, but basically they are the same.
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