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The usual dose is: Elderly patients and adults above 18 years: one capsule (300 mg erdosteine) twice a day. For oral use. The capsule must be swallowed whole with a glass of water. The maximum duration of therapy is 10 days. If you take more Erdotin than you should.
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erdosteine (Erdotin®) is not recommended for use within NHS Scotland as an expectorant for the symptomatic treatment of acute exacerbations of chronic bronchitis in adults. Evidence for the clinical efficacy of erdosteine is limited and was obtained from studies that do not reflect current practice for the management of chronic obstructive.
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Results: Patients with moderate COPD received erdosteine 300 mg twice daily (n=126) or placebo (n=128) added to usual COPD therapy for 12 months. During this time, there were 53 exacerbations in the erdosteine group and 74 in the placebo group, with 42.1% and 57.8% of patients, respectively, experiencing an exacerbation..
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A mucolytic. Used for. To help clear sputum in adults with chronic bronchitis. Also called. Erdotin®. Available as. Capsules. Mucolytic medicines, such as erdosteine, can be helpful to treat the symptoms of acute flare-ups in chronic bronchitis. Erdosteine works by making mucus (phlegm) less thick and sticky, and therefore easier to cough up.
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Identification Summary. Erdosteine is a mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD).. Generic Name Erdosteine DrugBank Accession Number DB05057 Background. Erdosteine is a drug that causes a breakdown of mucus, also known as a mucolytic agent. . It is a thiol derivative.
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Erdosteine is much more than a mucolitic drug; in fact is is a unique combination of four activities: • muco-modulatory activity: it improves mucociliary transport, sputum viscosity and mucus elasticity and reduces the sputum volume. • antioxidant activity: it reduces the levels of oxidative stress biomarkers and free radicals and increases the level of the endogenous antioxidant glutathione.
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Eksaserbasi akut bronkitis kronis, Gangguan pernapasan akut yang berhubungan dengan produksi lendir yang berlebihan, Gangguan pernapasan kronis yang berhubungan dengan produksi lendir yang berlebihan. Komposisi. Erdosteine 300 mg. Dosis. PENGGUNAAN OBAT INI HARUS SESUAI DENGAN PETUNJUK DOKTER. Dewasa: 1 kaplet, 2 - 3 kali per hari. Aturan Pakai.
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Erdosteine is a molecule with mucolytic activity. Structurally it is a thiol derivative characterized by the presence of two thiol groups. These two functional sulfhydryl groups contained in the molecule are released following first-pass metabolism with the conversion of erdosteine into its pharmacologically active metabolite Met-I. . The molecule has been discovered and developed in Italy by.
ERDOSTEINE ETERCON 300 MG STRIP 10 KAPSUL Kegunaan, Efek Samping, Dosis dan Aturan Pakai
Generic Name : Erdosteine. Up-to-date prescription details regarding Erdosteine are provided here. Understand it's uses, recommended dosages, its indications, how to take, when to take, when not.
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View erdosteine information, including dose, uses, side-effects, renal impairment, pregnancy and breast feeding.
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After administration of 300 mg, the peak plasma concentration of erdosteine (Cmax) -1.26 ± 0.23 ng/ml - was reached 1.18 ± 0.26 hour after administration (Tmax), while Ml showed a Cmax of 3.46 ^g/ml and a Tmax of 1.48 h. The plasma concentrations of erdosteine increase in a dose-dependent manner. Plasma concentrations of M1 increased also.
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The study demonstrates that patients taking erdosteine 300 mg twice daily experience a significant greater improvement in respiratory symptoms and quality of life, compared to control arm. These outcomes confirm that erdosteine can be an effective treatment against persistent COVID-19 symptoms and can avoid the complications of Long COVID-19.
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In 237 patients with an infective exacerbation of chronic bronchitis, erdosteine (300 mg twice daily) or placebo in association with amoxicillin (1500 mg/day) were administered for a maximum of 10 days . Eleven patients were lost due to different reasons. Clinical symptoms such as breathlessness, cough, and sputum viscosity improved more.
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Erdosteine, is an orally administered mucolytic agent. It is classified as a thiol derivative and produced for the management of symptoms caused by chronic obstructive bronchitis. Erdosteine contains sulfhydryl groups which are released after hepatic first-pass metabolism in the liver. Its active metabolites (3 in number) exert both mucolytic.
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Erdotin 300mg capsules are a medicine that helps to break down and clear the mucus in the lungs of people with chronic bronchitis. This leaflet provides important information for patients, such as how to take the capsules, possible side effects and precautions. Read it carefully before using Erdotin 300mg capsules.
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Skin and subcutaneous tissue disorders. Uncommon ( (≥ 1/1,000 to <1/100) Angioedema and cutaneous hypersensitivity reactions, such as urticaria, erythema, oedema and eczema. 5. Pharmacological properties. 6. Pharmaceutical particulars. 7. Marketing authorisation holder.